Monkeys reveal new clues toward elusive HIV vaccine and cure

first_img By Jon CohenMar. 9, 2018 , 11:50 AM BOSTON—Despite enormous efforts over more than 30 years, HIV/AIDS researchers have yet to develop either a vaccine or cure for the disease. But they have made progress in monkey experiments, and two studies reported here this week at the largest annual U.S. HIV/AIDS conference created serious buzz.Several AIDS vaccines have had some success in monkey models, which typically use SIV, a simian cousin of HIV that causes AIDS in rhesus macaques. But one vaccine has long stood out from the pack. Designed by Louis Picker and colleagues at Oregon Health & Science University’s Vaccine and Gene Therapy Institute in Beaverton, the vaccine stitches SIV genes into a harmless Trojan horse, cytomegalovirus. Picker’s team has given the vaccine to more than 200 monkeys and then “challenged” them with injections of a particularly nasty strain of SIV. All told, 55% of the animals became temporarily infected and then completely controlled the virus for years or even cleared it. Two stubborn questions remain, however: Picker and co-workers have yet to nail down the immune responses that explain the vaccine’s success, and they also can’t explain why it frequently fails.At the meeting this week—the Conference on Retroviruses and Opportunistic Infections—immunologist Michael Gale Jr. of the University of Washington in Seattle described how his group explored these questions by taking a big picture view of active genes in the protected and unprotected animals. Specifically, the researchers identified and compared clusters of genes in the two groups of animals that were turned on high or tamped down low. These clusters control the production of various interleukins (biochemicals that communicate messages between immune cells), cell growth, and inflammation. They drilled down to 234 genes that had different expression levels in the two groups at day 3 and found that by looking at these alone, they could predict with 91% accuracy whether the vaccine injection would protect an animal. “This is the most interesting talk at the whole meeting,” says Mario Clerici, an immunologist at the University of Milan in Italy who long has focused on why some humans handle the virus better than others.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Picker says these findings offer him new ways to tweak his vaccine. “Obviously the vaccine is tickling something, and maybe the critical issue is tickling a certain pathway a little bit stronger,” he says. As an example, he points to the genes that collectively control interleukin-10 production, which were turned on much higher in protected animals. “If that signal turns out to be critical, I can manipulate it,” he says. Picker has co-founded a company, Vir Biotechnology in San Francisco, California, that plans to start testing the vaccine in humans next year.On the cure front, immunologist Dan Barouch, who directs the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center–Harvard Medical School in Boston, threw the kitchen sink at the virus. His team first infected 44 monkeys with a hybrid of SIV and HIV called SHIV. One week later, the scientists began treating all the animals with antiretrovirals (ARVs) and continued for 2 years. In all 44 monkeys, the virus dropped to undetectable levels on standard blood tests. The researchers then divided the animals into four groups that received either nothing (the controls), a potent HIV antibody, a drug that binds to toll-like receptor 7 (TLR7) that studs innate immune system cells, or the antibody plus the TLR7 drug. Sixteen weeks later, they stopped all ARVs.In humans who control HIV with ARVs to the point that researchers cannot find the virus in their blood or tissues, the virus always comes screaming back, usually within a few weeks, once they stop taking drugs. That’s precisely what happened in all 11 control animals. In the monkeys given the TLR7 drug or the antibody, 20 of 22 no longer could suppress the SHIV. But in the group that received the antibody plus the TLR drug, five of 11 animals did not see the SHIV return after 6 months (the experiment is ongoing) and the others have low levels of the virus. “We’re very encouraged by this preliminary proof of concept study,” Barouch says.A key obstacle to curing an HIV infection is that even when people have undetectable levels of virus, a reservoir remains of cells that hold chromosomes laced with “latent” viral DNA, which doesn’t produce progeny and thus lies under the radar of the immune system—but can suddenly kick into gear and cause mayhem. Earlier monkey studies showed that the TLR7 drug can “shock” lately infected cells to produce the virus, setting them up for elimination. Many groups have attempted “shock-and-kill” experiments in monkeys and humans. “This is the first evidence that shock-and-kill works,” Picker says.Picker and others stress several important caveats. It’s possible that the virus will return in these five monkeys—humans presumed to be cured have had HIV show up more than 2 years after stopping ARVs. And in this experiment, ARV treatment was started a week after infection; it rarely happens that soon in people. SHIV is also easier for monkeys to naturally control than the SIV used in Picker’s studies. With all that in mind, Jeffrey Lifson, who does SIV studies at the U.S. National Cancer Institute in Frederick, Maryland, says the findings are “interesting, provocative, and potentially important.”Steven Deeks, a clinician who does cure trials at the University of California, San Francisco, says he soon plans to test a similar combination of a TLR drug and a potent antibody in patients who have been fully suppressed for several years. “There’s no clear mechanism here, but as a clinician, I don’t really care,” he says. “It’s all a big black box: You have something that goes in and something that goes out. What comes out here is no virus.” New studies in rhesus macaques, the main animal model used to study the AIDS virus, are showing the way forward for both a vaccine and a cure. Monkeys reveal new clues toward elusive HIV vaccine and cure Brennan Linsley/AP Photo last_img read more

De Rossi back for Boca

first_img Watch Serie A live in the UK on Premier Sports for just £11.99 per month including live LaLiga, Eredivisie, Scottish Cup Football and more. Visit: Daniele De Rossi has been declared fit enough to feature in Boca Juniors’ squad for the Superclasico with River Plate on Wednesday. De Rossi has played just five games for Boca since arriving in July due to a hamstring problem, which has kept him out for the past month. However, the former Roma midfielder has been called up for the second leg of his side’s Copa Libertadores semi-final with River, who lead 2-0 on aggregate. If he can prove his fitness, the 36-year-old may be considered for a farewell appearance with Italy during the international break in November. The derby is given the nickname ‘Superclasico’ because of the intense rivalry between the two Argentine clubs. They are both based in Buenos Aires and vied for the title of South America’s best in the Copa Libertadores Final last season.last_img read more

Delhi takes to kick-boxing. Here’s where you can lick them or join them

first_imgHilary Swank boxed her way into the Oscars. Uma Thurman impressed Bill and the rest of the world with her high kicks. Now it’s Delhi’s turn to get fighting feet. City studios have been sparring with one another to lure fitness fiends and PYTs to don boxing gloves.Forget the Oscars,Hilary Swank boxed her way into the Oscars. Uma Thurman impressed Bill and the rest of the world with her high kicks. Now it’s Delhi’s turn to get fighting feet. City studios have been sparring with one another to lure fitness fiends and PYTs to don boxing gloves.Forget the Oscars and the blood and gore. If you want to kick some serious butt and look good doing it, get into the ring. Kickboxing is the new fitness fetish.First, let’s get all the facts straight. “Kickboxing as an athletic workout includes shadow boxing, kicking and heavy bag work complemented by strengthening and conditioning drills,” says instructor Robin Gogoi of Club Xcell.It can best be described as a mixture of karate and boxing, another east meets west trend. The traditional form of kickboxing, Muan Thai-popularly known as Thai boxing-is a full-contact martial art. The winner in a competition is determined only when the opponent is annihilated. Translation: possible death.In contrast, the modern version is a semi-contact sport. Those who swear by this workout don’t actually have to fight one another in any ring. Kickboxing allows them to enjoy all the benefits without actually sparring or spilling blood-burning fat, toning muscle, enhancing metabolic rate, achieving greater agility and flexibility, and, of course, a figure to die for.Body Force GYM Ring leader Get in the ring with trainer Edward Noordanis (left) and his class for an actual fightEdgar Noordanis means serious business with his weekend Thai boxing classes. He is undoubtedly the most professional trainer in Delhi and ridicules the city’s airconditioned studios. “I train my students outdoors and even hold classes during the blistering heat of May and June,” says this Dutch trainer who learnt Muan Thai in 1984 in Holland. One visit to his back garden and you know exactly what he’s talking about. He actually has a boxing ring there. Ten bags are hung around the boxing ring. “Different bags have different purposes- a hard, low hanging bag works for the shin, a six feet long bag is meant for combination work, and speed bags are purely for elbow work,” explains Noordanis proudly.The warm-up routine is clearly written for all to see on one wall of his shed. “You can’t throw a good punch if you’re unfit. So everybody has to run at least three kilometres on a dirt track, no matter how long it takes. That’s followed by 10 minutes of skipping, 200 sit-ups and 10 minutes of stretching. Mind you, that’s just the first hour,” says Noordanis. After a short water break, the second hour is for “bag work.” On Sundays, students fight in the ring. In spite of his rigorous workout, Noordanis has had 300 students in the last four years. “Rules are not bent even for new students,” he says. Only proving that his claim of a 10 kg weight loss in the first month is not just fluff. Fees: Rs 150 per class. Tel: 9810194427.Club Xcell advertisementHigh jinx Robin Gogoi incorporate self defence in their kickboxing classesTrainer Robin Gogoi has chalked out his aerobic and anaerobic kickboxing programme scientifically, an attribute he learnt from his Japanese karate grandmaster Haya Shi. This karate black beltholder describes the former as “aerobics topped with karate and boxing.” The anaerobic class is comparatively faster and is meant for people used to the regime. Saurabh Vig incorporate self defence in their kickboxing classes”This is a more intense class which utilises the chemical system of the body,” explains Gogoi. New students work on punching, kicking, striking and blocking. Only after they have familiarised themselves with the basic moves are they allowed to try out these techniques with music.”Kickboxing unites the mind, body and spirit, says Gogoi who ends his classes with a martial art meditating position, Seiza, where one squats on the knees with eyes shut. Gogoi also has an hour-long self-defence class that is a hit with women. Fees: Rs 1,815 per month. Tel: 9810259501.FitnesolutionFighting feet Kiran Sawhney of Fitnesolution believes that kickboxing helps one achieve perfect mind and body coordinationKiran Sawhney started this studio just 10 months ago and holds her kickboxing classes with her trainer pal Saurabh Vig. “Kickboxing has become a popular workout as it teaches one to stay positive,” says Sawhney. Judging from her batch of 20 trainees, there is clearly no age-bar for this exercise. “I even have a 60-year-old in my class,” she exclaims. Even though kickboxing is not a martial art per se, Sawhney believes that “it can come in handy when one is in a vulnerable situation.” She also makes it a point to give students tips on self defence. “The rules of a ring don’t apply in real life. The knees and elbows are our most powerful weapons. I always tell my students that if they are ever mugged, they should kick and punch the attacker’s groin,” says Sawhney, who is saving up to buy speed-bags for her studio. Fees: Rs 2,000 per month. Tel: 9810530027.Studio 8To really tone up those muscles, Vineeta Sarkar combines her kickboxing class with the gym ball and weightsVineeta Sarkar is on cloud nine. Her studio is a great hit with women in Gurgaon. “My kickboxing classes have become so popular that my students are constantly pressuring me to allot more classes, especially during the weekends,” she says. “A regular class begins with simple movements. As the tempo builds up, so does the complexity of the workout. Later, the class slows down again and students move to stretching their legs, arms and back to increase mobility. To really tone up those muscles, the last half hour of the session is devoted to the gym ball and weights.”Sarkar learnt her skills at the American Aerobics Fitness Association in San Diego. She claims her classes give her students “lean legs, sculpted arms and a flexible body”. No wonder she’s in such demand. Fees: Rs 2,000 a month. Tel: 9810202919.advertisementlast_img read more

Bangladesh drop Shafiul Islam for second Test against England

first_imgBangladesh have drafted uncapped all-rounder Mosaddek Hossain and pacer Subashis Roy for the second Test against England.The selectors left out pacer Shafiul Islam when they announced a 15-strong squad late on Monday for the Mirpur Test, reports hosts lost the first Test by just 22 runs in Chittagong in what would have been an epic win in their Test history.Shafiul Islam bowled just 12 overs in two innings in the first Test. His influence on the English batsmen was minimal and he did not claim any wicket.Pacer Kamrul Islam Rabbi, who earned his first Test cap in the opening Test, retained his spot.He gave away 41 runs from eight overs in the first innings but did well with the old ball in the second innings. He dismissed Jonny Bairstow to break a crucial century stand.While the selectors have kept a combination including two pacers in the equation, the inclusion of Mosaddek, another offspinner all-rounder, indicates it would be another turning track in Dhaka.The second Test begins on Friday at the Sher-e-Bangla National Cricket Stadium.Squad: Mushfiqur Rahim (captain), Tamim Iqbal, Imrul Kayes, Mominul Haque, Mahmudullah, Shakib Al Hasan, Mehedi Hasan Miraz, Sabbir Rahman, Soumya Sarkar, Taijul Islam, Shuvagata Hom Chowdhury, Kamrul Islam Rabbi, Nurul Hasan, Subashis Roy and Mosaddek Hossain.last_img read more

No room at the top in Tests for ODI match-winner Martin Guptill

first_imgMartin Guptill will not be included in the New Zealand squad for the upcoming Test series against South Africa despite a brilliant match-winning innings in the one-dayer against the Proteas on Wednesday.Guptill, playing for the first time in a month after two hamstring injuries, scored 180 not out in the seven-wicket victory over the tourists in Hamilton to level the five-match series at 2-2.Even the third highest one-day international score by a New Zealander was not enough to earn Guptill a Test recall as an opener, coach Mike Hesson said, but the 30-year-old could soon press a case for inclusion in the middle order.”The Test team is performing pretty well at the moment,” Hesson told reporters on Thursday.”Martin and I have talked about Test cricket a lot and we certainly gave batting at the top of the order a decent crack. Certainly batting in the middle order is something we are keen to explore and he will do that first with Auckland.”Guptill has played 47 Tests, 40 of them in the top order, but has struggled to convert his success in limited-overs cricket into the longer format.While his ODI average is 43.98, and Wednesday’s effort gave him all three of New Zealand’s top scores in the format, his Test average is 29.38. (Martin Guptill was unstoppable, says AB de Villiers)Guptill’s technique has been exposed in Test matches, where he has been vulnerable to deliveries moving away outside off stump or short-pitched bowling.South Africa have been particularly ruthless at exploiting that weakness, with his average against the Proteas in seven Tests just 14.38.advertisementHe averages 27.49 batting in the top order but in the middle order, where the ball tends to move less, his average is a far healthier 43.37.Hesson said that while Henry Nicholls had earned the right to hold on to the number five spot that Guptill would be looking to fill, good form in domestic cricket was difficult to ignore.”It’s something that Martin is really keen to have a crack at and certainly something that we are keen for him to explore at first class level first,” Hesson told Radio New Zealand.”Hopefully get some success in that and then… there might be a (test) opportunity down the line.”The final one-day international is on Saturday at Eden Park with the first test starting in Dunedin on March 8.last_img read more

Less Is More: 4 Tips for Great Year-End Appeals

first_imgThe final two months of the year, and especially the end of December, are prime time for donors to give. With so much competition for their attention, it’s vital to send appeals that quickly draw donors into your mission and inspire them to take action.In our Nonprofit 911 webinar Crucial Year-End Giving Strategies, Mazarine Treyz, author of Wild Woman’s Guide to Fundraising, shared how a few simple changes in word choice and formatting your appeal can mean the difference between reading and deleting.Be Present, Active, and DirectPresent-tense verbs spark people into action. Strengthen those verbs with active voice and first-person pronouns. Minimize adverbs, adjectives, and qualifiers.Look at how the verbs in this opening passage bring you into the experience: “Go on. Pick up the pen. Write a check now.” All present tense. The words you choose can paint a strong and direct picture for your donors: “This child is hungry now. You can help her now. Please give.” That’s a clear and present call to action. Speaking of which…Move Your Call to Action Front and CenterLots of nonprofits save their call to action for the end of the appeal. Instead, pepper your request throughout your letter. Offer donors several moments to think about giving. If you’re sending an email appeal, be sure to link those calls to action to your donate page, if appropriate.Focus on the DonorIt really is all about you—the pronoun, that is. Use it throughout your appeal: “Can you help us? There is hope, and that hope is you.” Talk about how donors have made the world better with their gift: “You took 50 kids off the street last year with your donation, and now you can do more.” The donor becomes the hero of this story, increasing odds that she’ll click the donate button or send you a check because you acknowledged her important role in your mission.Avoid Common Formatting MistakesHow you present your message is just as important as the words you choose. Here are three common formatting mistakes that prevent donors from reading your appeal and taking action:Long, unbroken paragraphs.Tiny fonts.Tight spacing between lines of text.You have a small window of time to grab your donor’s attention and make your case. These simple changes help make your appeal easier to read and deliver greater impact:Increase font size, and break long paragraphs into shorter ones.Turn a long paragraph into a bulleted list.Spotlight key ideas or messages with boldfacing or yellow highlighting.Feature a quote in larger text from a person the donor is helping.Use readable fonts for the body of your letter. Try a sans serif like Arial for online or email appeals and a serif font like Times New Roman for postal mail.As you write and revise your year-end appeal, ask yourself, “How does our appeal letter look right now? Is there anything on this list that we could apply to make it easier for donors to read and act on?” And be sure to download the Nonprofit 911 webinar, Crucial Year-End Giving Strategies with Mazarine Treyz, for even more great tips and resources.If you need more help with your year-end appeals, download our guide.last_img read more

Urban Meyer’s Daughter Has A Message For Jim Harbaugh

first_imgohio state head coach urban meyer after his final gamePASADENA, CA – JANUARY 01: Ohio State Buckeyes head coach Urban Meyer celebrates winning the Rose Bowl Game presented by Northwestern Mutual at the Rose Bowl on January 1, 2019 in Pasadena, California. (Photo by Harry How/Getty Images)Michigan head coach Jim Harbaugh took a shot at former Ohio State head coach Urban Meyer this week, claiming that “controversy” has followed him throughout his career.“Urban Meyer’s had a winning record. Really phenomenal record everywhere he’s been,” Harbaugh said on The Athletic’s The TK Show podcast Thursday. “But also, controversy follows everywhere he’s been.”Harbaugh didn’t back down from his comment during his Big Ten Media Days press conference, either.“I don’t think it was anything that was new, or anything of a bombshell,” Harbaugh said. “It’s things that you all understand and have written about.” Meyer retired from Ohio State at the end of 2018 following a season clouded by the Zach Smith domestic violence scandal. Meyer had previously coached at Florida, where several of his players dealt with off-the-field legal issues.Harbaugh, of course, is 0-4 against Meyer and Ohio State, so his comments are seen as sour grapes by many, including Nicki Meyer Dennis.“Wait guys maybe this is a deflection strategy! Throw a little mud to avoid answering why you always lost. #RespectTheRivalry 7-OH (0-4 lol),” she wrote.Harbaugh, while not necessarily wrong with his comment about Meyer, is certainly going to have to face more questions about it heading into the 2019 rivalry game against Ohio State.Michigan is set to host Ohio State in Ann Arbor on Nov. 30.last_img read more

World Cup 2019: Angelo Mathews wants Sri Lanka to ’embrace the challenge’

first_imgWorld Cup 2019: Angelo Mathews wants Sri Lanka to ’embrace the challenge’Stating that the players are not new to conditions in England, Sri Lanka veteran Angelo Matthews said it was the occassion and the nature of the tournament that would make the difference.advertisement Indo-Asian News Service LondonMay 28, 2019UPDATED: May 28, 2019 09:09 IST Most players in Sri Lankan team are coming back into the ODI side after lengthy spells on the sidelines (AP Photo)Sri Lanka’s Angelo Matthews has urged his teammates to not let pressure situations get to them and play with freedom. Sri Lanka, who won the World Cup in 1996 and were runner-up in 2007 and 2011, come into the 2019 edition of the tournament as rank under-dogs.Moreover, most players are coming back into the ODI side after lengthy spells on the sidelines, including captain Dimuth Karunaratne who has not played an ODI since 2015.”In a big tournament like this, you’ve got to play with freedom and embrace it, rather than putting too much pressure on yourself,” Matthews is quoted as saying by the ICC.”Yes, it’s a World Cup, you have to perform well to win it. But at the same time you have to embrace the challenge. If you put a lot of pressure on yourself, it adds to your burden. Try and embrace it, look at it as an opportunity to perform, to do something better for the country,” he said.Stating that the players are not new to conditions in England, Matthews said it was the occassion and the nature of the tournament that would make the difference.”The biggest challenge will be in overcoming pressure situations,” Matthews is quoted as saying by the ICC. “Quite a lot of us have played in England and we know the conditions. But handling the pressure and the situations well is going to be the challenge,” he said.Meanwhile, Sri Lanka legend Mahela Jayawardene on Monday criticized former captains Mathews and Dinesh Chandimal by saying that both had become the victims of ‘cricket politics’. Soon, Mathews took to Twitter to respond to Mahela’s charges.advertisementMathews was the skipper of Sri Lanka across formats when Mahela announced his retirement in 2015 but since then the Lankan captaincy has resembled a game of musical chairs with Chandimal, Thisara Perera, Lasith Malinga, Chamara Kapugedara and lately Dimuth Karunaratne getting a chance to lead the side. The phenomenon has also coincided with declining results for the side in white-ball cricket.Defending his role during the captaincy stint, Mathews took to Twitter on Sunday and agreed that everyone including Mahela ‘has their opinion’ while urging his senior to help the team ‘with his knowledge and encouragement’ during the upcoming World Cup.”Thanks for the concern guys everyone has their opinion and mj (Mahela Jayawardene) has his too.suprised to see some of his comments while denying them my top priority now is the World Cup and I urge mj to help us with his knowledge and encouragement in this crucial time which will mean a lot Thankyou”: Mathews wrote on Twitter.Also read | Surprised by Jayawardene’s comments: Angelo Mathews responds to captaincy criticismFor sports news, updates, live scores and cricket fixtures, log on to Like us on Facebook or follow us on Twitter for Sports news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byrohan sen Tags :Follow Angelo MathewsFollow Sri Lanka cricket teamFollow World Cup 2019last_img read more

May 2014 Report Released

first_imgGovernment is taking too long to correct known deficiencies in its programs, acting Auditor General Alan Horgan said in his May report released today, May 21. “Only 50 per cent of the performance audit recommendations we made in 2010 and 2011 have been implemented,” said Mr. Horgan. He also said the public accounts committee will begin formally endorsing his recommendations and ask the government’s audit committee to oversee implementation. He noted he is hopeful that this will help improve results. Mr. Horgan identified concerns with the public drinking water supply program. The acting auditor general said there are differences in how inspectors carry out their audit work and not all deficiencies are recorded or revisited to ensure concerns have been addressed. “Guidance for inspectors is limited in certain key areas,” said Mr. Horgan. “Some inspectors do not examine supporting documentation to verify that issues have been addressed.” The Department of Environment is also not using its IT system to its potential in managing the public drinking water supply program. Improvements could be made to help better identify risks to safe drinking water. An audit of the public school system’s student information system identified critical weaknesses. “My office’s IT audit team was able to gain unauthorized access to the iNSchool system and view confidential information such as student grades, addresses and health issues,” said Mr. Horgan. He also noted the Department of Education and Early Childhood Development has corrected the weaknesses his office used to gain access. “Our audit found a number of appropriate controls in the system, and I believe the department and the school boards used reasonable processes in the design, procurement and implementation of the iNSchool system.” The acting auditor general found the Department of Health and Wellness is doing a poor job of monitoring certain types of payments to physicians. “The department does not know whether physicians receiving payments under the academic funding plan and alternative payment plan are meeting all their contract requirements,” said Mr. Horgan. Health and Wellness contracts with an external company to audit payments to physicians. But the acting auditor general found the department requests too few audits of academic funding and alternative payment arrangements. Mr. Horgan also said that when issues are identified, the department does not follow these up in a timely manner. On another audit, Mr. Horgan said Communications Nova Scotia’s advertising and other communications are generally non-partisan. But he identified serious deficiencies in how the agency manages procurement. “The majority of the procurements we tested had issues,” the auditor general said. “Communications Nova Scotia needs to pay closer attention to procurement rules and do a better job of following those rules.” Another audit identified concerns with managing mineral resources by the Department of Natural Resources. Security collected to ensure operators clean up their mine sites may not be sufficient and the department does not regularly update its clean-up estimates. Ensuring the collection and accuracy of royalty payments for mined minerals also needs work. The acting auditor general found payments were not always calculated correctly. The 113-page report contains 71 recommendations to government. The full report is available at .last_img read more

2009 Swiss aircraft buy CBI books Sanjay Bhandari IAF officials

first_imgNew Delhi: The Central Bureau of Investigation (CBI) on Saturday said it had a registered a case against arms dealer Sanjay Bhandari, officials of Swiss company Pilatus Aircrafts Ltd and some unknown officials of the Indian Air Force and the Defence Ministry in the 2009 trainer aircraft deal case. After registering the FIR, the investigating agency conducted searches on the premises of Bhandari in connection with the 2,895.63-crore deal. Bhandari is already being investigated for allegedly buying a benami house for Congress President Rahul Gandhi’s brother-in-law Robert Vadra in London. Also Read – IAF receives its first Rafale fighter jet from France A senior CBI official told IANS: “A case was registered on Wednesday against Bhandari and Bimal Sarren, both directors of Offset India Solutions Pvt Ltd, as well as officials of Swiss-based plane-maker Pilatus Aircrafts Ltd over alleged irregularities in procurement of 75 basic trainer aircraft in 2009.” The CBI said the Indian Air Force on December 16, 2009 issued a request proposal for procurement of 75 basic trainer aircraft and Pilatus Aircrafts Switzerland was one of the bidders. Also Read – Cosmology trio win Nobel Physics Prize “To obtain the contract for supply of 75 basic trainer aircrafts to IAF, Pilatus Aircrafts entered into a criminal conspiracy with Bimal Sareen and Sanjay Bhandari by fraudulently signing a Service Provider Agreement with the latter in June 2010 in violation of the Defence Procurement Procedure 2008,” the CBI alleged. The agency further alleged that kickbacks up to Rs 339 crore were paid in the deal to influence some unknown IAF and Defence Ministry officials, who were associated with the procurement process. From 2011 to 2015, Pilatus Aircrafts made the payment in the bank accounts of Dubai-based company Offset India Solutions FZC, belonging to Bhandari, to obtain the contract, the CBI said. The CBI on November 11, 2016 initiated a preliminary enquiry (PE) into the deal to verify the bribery charges. The CBI official said the agency was probing the kind of services that Offset India Solution Pvt Ltd provided to the Swiss aircraft firm. Following the probe, the CBI filed an FIR under various provisions of the Indian Penal Code dealing with criminal conspiracy and cheating, and the Prevention of Corruption Act. Bhandari’s companies Offset India Solutions Private Limited and Dubai-based Offset India Solutions FZC, as well as his associates Himanshu Verma, Deepak Agarwal and an unknown man have also been named as accused in the case.last_img read more

Company director arrested for swindling Rs 345 crore

first_imgNEW DELHI: The Delhi Police’s Economic Offences Wing (EOW) has arrested Awanish Kumar Mishra, Director of Allied Financial Services Pvt Ltd (AFSPL) for alleged misappropriation of funds to the tune of Rs 345 crore.An official said Mishra had forged the signatures of the authorised signatories of the complainant company to carry out the fraud. The EOW had registered a case under the sections of criminal conspiracy, cheating and fraud against Mishra on March 26, this year on the complaint of Sanjeev Gemawat, Executive Director of Dalmia Cement. Also Read – After eight years, businessman arrested for kidnap & murderGemawat registered the case alleging that AFSPL, Money Mishra Overseas Pvt Ltd, National Securities Depository Ltd (NSDL) and IL&FS Securities Services Ltd (ISSL) have duped them. In the complaint to the police, Gemawat said that Dalmia Cement was holding securities or mutual funds worth Rs 344.07 crore in two Demat accounts with AFSPL. These were allegedly fraudulently transferred on forged documents and pledged with another company. In his complaint, Gemawat alleged, “Our erstwhile subsidiaries, OCL India Limited (OCL) and Dalmia Cement East Limited (DCEL) were interested in making mutual fund investments in 2017. We availed the services of NSDL and its participant AFSPL. Accordingly, we opened our Demat accounts in the name of DCEL.” Also Read – Two brothers held for snatchings”After making the initial investment, several further investments and redemption were made from our Demat accounts and we were holding securities worth around Rs 344.07 crore in these accounts. AFSPL also sent periodic statement of our accounts and kept us informed of the current status of our accounts,” Gemawat said in the complaint. “We decided to redeem our securities and submitted redemption requests on December 27 last year to AFSPL. In response, they informed us that our request of redemption had been sent to the clearing agent ISSL, who did not release the same on time,” he said in the complaint. It has been further alleged that despite receiving assurance on redemption after their e-mail request for the same, AFSPL did not honour them. “After some time, we approached NSDL and they informed us on January 17 that there were no securities available in our Demat accounts. However, the Director of AFSPL simultaneously sent an e-mail on January 31 where he had confirmed that we are holding securities in our two Demat accounts,” the complaint read.last_img read more

FADA asks SIAM to start reporting monthly sales data on basis of

first_imgNew Delhi: Automobile dealers’ body FADA has asked its auto industry counterpart SIAM to start reporting monthly sales data on the basis of actual registrations based on road ministry’s Vahan platform instead of wholesales. In a letter addressed to Society of Indian Automobile Manufacturers (SIAM) President Rajan Wadhera, FADA President Ashish Harsharaj Kale said reporting retail numbers is also a norm which is followed internationally and would help in the betterment of the Indian auto industry as well. Also Read – Thermal coal import may surpass 200 MT this fiscal”Both dealers and component manufacturers also felt that it would have been easier to predict the ongoing slowdown in auto sales if retail numbers were reported, helping all in their inventory management and would have kept all better placed in facing these dynamic times,” Kale wrote in the letter. FADA has been advocating this from November 2018 and many of its members have also done the same with their respective original equipment manufacturer (OEM’s) and have received a positive response of accepting it, given if it becomes an industry practise, he added. Also Read – Food grain output seen at 140.57 mt in current fiscal on monsoon boost”Hence, I request you to please use your good offices to impress upon all the members of SIAM as well to report retail sales which is now available in VAHAN, instead of factory despatches and graduate to market share calculation of the industry and of dealer partners by registration data instead of wholesale despatches,” Kale noted. As per the data released by SIAM earlier this week, vehicle sales across categories, including passenger vehicles (PVs) and two-wheelers and commercial vehicles (CVs) saw steepest fall on record by 23.55 per cent at 18,21,490 units in August as against 23,82,436 units in August 2018. Similarly, domestic PV sales saw its worst-ever fall in two decades last month, slumping by 31.57 per cent to 1,96,524 units from 2,87,198 units in the year-ago period. On the other hand, August retail sales data showed a somewhat better picture in terms of sales pointing to inventory correction taking place in the industry. As per retail sales data also provided by SIAM, total automobile sales declined by 4.15 per cent to 16,00,376 units as compared with 16,69,751 units in August 2018. Similarly, PV sales stood at 2,38,357 units last month as compared with 2,56,662 units in the same month of last year, a decline of 7.13 per cent.last_img read more

Liberal info bill could hinder Indigenous land claim efforts watchdog tells MPs

first_imgOTTAWA – The Trudeau government’s proposed changes to the Access to Information Act could hamper efforts to settle Indigenous land claims, the federal information watchdog says.Legislation that would give government agencies more leeway to refuse to process access requests would make it tougher for Indigenous groups to obtain the historical records they require, information commissioner Suzanne Legault told a House of Commons committee Wednesday.Legault is critical of provisions that would allow an agency to reject a request unless the applicant stated the type of record being sought, the subject matter and the time-frame in which the documents were created — criteria she considers unreasonably specific.For instance, a requester might not know the date a property title they seek was drafted — but that missing information could disqualify the request.Legault said under the new scheme it “would be a lot more difficult for First Nations to access the information that they need” to establish land claims or document past events at the centre of disputes.New Democrat MP Nathan Cullen said her response “should weigh on all of us as we consider amendments to this bill.”The access law allows applicants who pay $5 to ask for government documents ranging from expense reports and internal audits to briefing papers and archival papers, but it has been criticized as clumsy and antiquated.The Liberal government says the bill, introduced last June, represents the first real modernization of the law since it took effect in 1983.Transparency advocates have told the MPs on the information, privacy and ethics committee that the new powers to refuse requests would create barriers for people seeking federal files.Legault says she has already received at least one complaint about an agency applying the new criteria, even though the bill is still before committee.The requester asked National Defence for correspondence between two named individuals within a 10-week period. Defence took the position that since the request did not specify a subject matter, it would not process the application.Legault maintains the request was not difficult to understand or to process, nor would it have unreasonably interfered with the department’s operations. Following the requester’s complaint and the information commissioner’s intervention, Defence agreed to process the request.Legault told the MPs an access request from the Globe and Mail newspaper that unearthed key information relating to the Liberal sponsorship scandal of the Jean Chretien era could have been refused if the new criteria were in place, since the request related to several years of budgetary records.She said the proposed provisions were “a regression for Access to Information rights generally.”Liberal MP Frank Baylis took issue with her assessment, calling the criteria “exceedingly reasonable.”Overall, however, committee members have signalled a willingness to entertain changes to the bill following widespread criticism that it falls short of Liberal transparency promises.In a report presented to Parliament in September, Legault said the bill would take people’s right to know backwards rather than forward.The government has not fulfilled its promise to extend the law to the offices of the prime minister, cabinet members, senators, MPs and administrative institutions that support Parliament and the courts, she said.Instead, these offices and institutions would be required to regularly release certain types of records, such as hospitality and travel expenses and contract information.Such a scheme allows government to decide what information Canadians can obtain, rather than letting requesters decide for themselves, Legault said. It also denies the commissioner any oversight of the process.In addition, the bill backpedals on a promise to give the information commissioner genuine power to make orders about the release of records, she said.— Follow @JimBronskill on Twitterlast_img read more

Trudeau continues steel tour with stops in Sault Ste Marie Regina

first_imgSAULT STE. MARIE, Ont. – Prime Minister Justin Trudeau will be in Sault Ste. Marie, Ont., and Regina today as he continues a tour of steel and aluminum plants to reassure workers there are measures in place to shield them from the possibility of U.S. tariffs.U.S. President Donald Trump recently exempted Canada and Mexico from tariffs of 25 per cent on steel and 10 per cent on aluminum, although the U.S. government has been dropping hints that the exception is only temporary.During his earlier visits to factories in Saguenay, Que., and Hamilton, Trudeau said the national security argument the U.S. has made when it comes to considering tariffs makes no sense and could not apply to Canada.Speaking in Hamilton on Tuesday, Trudeau said there are measures in place, including tariffs and tougher border controls, to prevent steel and aluminum producers in other countries from using Canada as a back door to slip cheap metal into the United States.Trudeau said the surplus of steel in the global market is not new and with American tariffs in place, some countries might try to ship their products to the U.S. through Canada.He said Canada would be alert to that and work with industry partners and the United States to make sure that doesn’t happen.A steel tariff would be devastating for Sault Ste. Marie, the heart of steel country in northern Ontario, where Algoma makes up more than 40 per cent of the city’s economic output.last_img read more


first_imgAdvertisement Facebook Login/Register With: Based on the Soulpepper production of Ins Choi’s award-winning play, KIM’S CONVENIENCE is the funny, heartfelt story of The Kims, a Korean-Canadian family who run a convenience store in downtown Toronto. The series centres around Mr. and Mrs. Kim (‘Appa’ and ‘Umma’), who immigrated to Toronto in the ’80s to set up shop near Regent Park, and their two grown kids, Jung and Janet. The world of Kim’s Convenience is real, colourful and urban – a diverse landscape of people and places – with the Kim family at its core, as they find humour in their everyday lives running the store.KIM’S CONVENIENCE airs Tuesdays at 9 p.m. (9:30 NT) on CBC and is also available to stream online at The series’ first season finale will air at a special time at 8 p.m. (8:30 NT) on Tuesday, December 27, featuring two back-to-back episodes.Produced by Ivan Fecan and co-created by Ins Choi and Kevin White, KIM’S CONVENIENCE stars Paul Sun-Hyung Lee (Shoot The Messenger, Degrassi: The Next Generation) as Appa, Jean Yoon (Orphan Black, The Expanse) as Umma, Simu Liu (Blood and Water, Taken) as Jung, Andrea Bang (Camp Death III: The Final Summer) as Janet, Andrew Phung (Adventures of a Pizza Guy) as Kimchee, and Nicole Power (Anne of Green Gables) as Shannon.The series is executive produced by Ivan Fecan, Tim Gamble, Alexandra Raffé, Leslie Lester, Albert Schultz, Ins Choi and Kevin White, with Sandra Cunningham and Robin Cass (Strada Films) serving as supervising producers.*Source: Numeris TV Meter, October 11 – November 29, 2016, CBC Total, A2+, Total Canada, AMA, generated by InfoSys+TV-30-SOCIAL MEDIA LINKS:Twitter: @KimsConvenienceInstagram: @KimsConvenienceFacebook: CBC/Radio-CanadaCBC/Radio-Canada is Canada’s national public broadcaster and one of its largest cultural institutions. We are Canada’s trusted source of news, information and Canadian entertainment. Deeply rooted in communities all across the country, CBC/Radio-Canada offers diverse content in English, French and eight Indigenous languages. We also provide international news and information from a uniquely Canadian perspective. In 2017, CBC/Radio-Canada will be at the heart of the celebrations and conversations with special 2017-themed multiplatform programming and events across Canada.For more information including series synopses, press releases, hi-res images and bios, please visit the CBC Media Centre at Thunderbird EntertainmentThunderbird Entertainment is a rapidly growing Vancouver-based multiplatform entertainment company with offices in Los Angeles, Toronto and London. Thunderbird creates award-winning programming for Canadian and International broadcasters and boasts divisions in scripted and unscripted development and production, theatrical distribution, and animation.Thunderbird’s most recent projects include Blade Runner 2049 starring Ryan Gosling and Harrison Ford, hit Canadian comedy Kim’s Convenience, recently announced dramatic series Somewhere Between for ABC and the animated Netflix original series Beat Bugs, featuring reimagined songs from the Beatles catalogue featuring artists such as Sia, Eddie Vedder and P!nk.About SoulpepperLocated in its multi-venue home, the Young Centre for the Performing Arts in Toronto’s Distillery Historic District, Soulpepper is Toronto’s largest not-for-profit theatre company. Founded and guided by artists, under the leadership of Artistic Director Albert Schultz and Executive Director Leslie Lester, Soulpepper has an integrated mission which includes: industry-leading youth outreach initiatives; the Soulpepper Academy, Canada’s only multi-year paid professional training program for theatre artists of all disciplines; and a year-round diverse repertory season which is grounded in the classics and committed to the creation of new works, new forms, and innovative practices. Visit for more details. Advertisement LEAVE A REPLY Cancel replyLog in to leave a comment CBC today announced the renewal of its breakout hit comedy series KIM’S CONVENIENCE, following an acclaimed first season (13 x 30) that is drawing an average audience of 933,000 per episode to date (2+ AMA), with 39% of viewers in the 25 – 54 demographic.* A CBC original series produced by Thunderbird Entertainment (Thunderbird) in association with Soulpepper, the series will return with Season 2 (13 x 30) in fall 2017.“Canadians have fallen in love with the Kims. The series has struck a chord among viewers of all ages with its unique perspective and its authentic, relatable and hilarious take on family relationships,” said Sally Catto, general manager, programming, CBC. “We couldn’t be more thrilled with how CBC audiences have responded to the series and its talented cast, and look forward to partnering with Thunderbird and Soulpepper to bring fans a second season in 2017.”“All of us at Kim’s have loved making this show and are enormously gratified that it has connected with audiences so viscerally, “ said the series’ producer, Ivan Fecan. “We can’t wait to start work on season two.” Advertisement Twitterlast_img read more

Casual picture of King Mohammed VI in New York goes viral

first_imgNew York- A casual picture of King Mohammed VI, which was posted on social media on Tuesday, is going viral with several thousands of Moroccans sharing on Facebook and twitter.The picture shows King Mohammed VI in an apparel store with a Moroccan in New York. King Mohammed VI appears smiling besides a Moroccan who put his arm around the King’s neck.last_img

Tourists urged to boycott events rides in Sri Lanka using elephants

Tourists have been urged to boycott events and rides using elephants in Sri Lanka.The animal rights group, People for the Ethical Treatment of Animals (PETA), said that Sri Lanka is a fast-growing holiday hotspot, thanks to its stunning beaches, surf spots, and national parks. But for the country’s captive elephants, this rapid increase in tourism means only more suffering. “Until tourists stop paying to ride them, elephants will continue to face exploitation and abuse. If you’re visiting Sri Lanka, please refuse to ride elephants, avoid visiting any attraction that offers or endorses elephant rides, and steer clear of festivals in which elephants are paraded. This includes the Pinnawala Elephant “Orphanage”, Dehiwala Zoo, and Kandy Esala Perahera festival,” PETA said. (Colombo Gazette)<span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span> “Humans sit atop elephants in a howdah, a type of metal seat, which is strapped to the animals’ delicate backs. Elephants have sharp, bony protrusions that extend upwards from their spine, so the combined weight of the howdah, the tourists, and the mahout (handler) can cause them permanent, agonising spinal damage,” PETA said. PETA says elephants used for tourist rides – which are widely advertised across the country – are typically kept tightly chained and isolated from other elephants. Forced up and down the same busy roads day after day, they’re often worked to exhaustion in the sweltering heat – as soon as one group of tourists gets off, the next one gets on. PETA notes that elephants live in constant fear of the mahout, who controls them using a bullhook– a spear-like instrument with a sharp hook that’s commonly used to strike and injure them.Elephant “attractions” that chain the animals, use bullhooks, and offer elephant rides often describe themselves as “sanctuaries” or “orphanages” in order to dupe tourists into believing that they’re ethical. read more

Ad zapper annoys broadcast TV networks say device threatens economic structure

NEW YORK, N.Y. – The maker of a new DVR that lets consumers zap away broadcast TV commercials at the touch of a button suggested Tuesday that the networks are being short-sighted in opposing the technology.The Dish Network, which has offered its new Auto Hop feature on new digital video recorders sold in the U.S. since March, said it believes that people who buy the machine are watching more network television than they had before. The Auto Hop automatically records every minute of prime-time programming on ABC, CBS, NBC and Fox and stores it for eight days.“It’s a win-win for both consumers and the networks,” said Vivek Khemka, Dish Network vice-president of product management.That opinion is anecdotal, however. Dish officials say they don’t yet have hard data to back up the contention that more of their customers are watching network shows because they are automatically stored on their DVR.The Dish Network DVRs are not sold in Canada, though various products are available on the domestic market from cable providers and electronics retailers that allow users to fast-forward through the commercial breaks.U.S. network executives are angry about how Auto Hop allows viewers to eliminate commercials on the recorded shows through one button, no fast-forwarding required. It didn’t help their moods that Dish, the satellite service with about 14 million customers in the U.S., was advertising the new feature on the week that networks were touting their new fall programming. The feature isn’t available for cable network programming.Dish said Fox and NBC have refused to allow its ads for the new DVR on their networks.“Ads are key to our business, so we’re not supportive of anything that doesn’t support our advertisers,” said Paul Lee, president of the ABC Television Group.During a presentation to advertisers at Radio City Music Hall, Ted Harbert, chairman of NBC Broadcasting, called the Dish Network feature “an insult to our joint investment in programming.”In one respect, the issue is a rerun for TV networks. In 2001, they sued the maker of Replay TV, another DVR, to stop a similar feature. The feature wasn’t included in the next model of DVR that Replay TV put out, and the company that made them filed for bankruptcy before the lawsuit could be resolved.Kevin Reilly, Fox entertainment president, said it was surprising that Dish would make such a move against its largest content provider.“More broadcast is watched there than anything else, so this seems like a strange thing to do,” Reilly said. “But we’re still evaluating it.”Khemka said Auto Hop has features that are sensitive to the broadcasters’ concerns. The commercial zapping feature has to be activated; the recorded programs will still contain the ads if the button isn’t used. The feature also won’t allow the commercials to be skipped until at least 1 a.m. Eastern time the next day, and studies show that a significant amount of recorded programming is viewed the same night it airs.Dish has also supported broadcasters by paying significant rate increases for their content, said company spokesman Robert Toevs.If people are deciding between a cable or satellite provider, the feature gives the company a competitive edge, Khemka said. Indeed, Auto Hop is the feature that Dish focuses on during its current ad campaign.Dish said it’s exemplifying its belief in the advertising structure by spending tens of millions of dollars on television ads, the kind of ads customers would be allowed to zap through.At this point, Auto Hop is likely in the hands of relatively few viewers, but Dish wouldn’t say how many of their customers have it. As a point of comparison, an estimated 700,000 new homes signed up for Dish in the first three months of the year.The jury is also still out on the ultimate impact of ad skipping. Nearly half of American households with televisions now have DVRs, and there hasn’t been any measurable impact on the rates that advertisers are paying for broadcast commercials.Ratings indicate that DVR usage has increased viewership of some network TV shows, said Jack Myers, publisher of the industry newsletter The Myers Report. In an odd way, fast-forwarding through commercials often makes people concentrate more intensely on the TV and stop if something interests them, he said.Allowing a customer to eliminate the commercials entirely, however, is “too big a game-changer,” he said. “It brings to question Dish’s understanding of the fundamentals of broadcast television.” by David Bauder, The Associated Press Posted May 22, 2012 4:09 pm MDT Ad zapper annoys broadcast TV networks; say device threatens economic structure AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email read more